But he answered the one who was speaking to him and said, “Who is my mother, and who are my brothers?”
With this question, Jesus emphasizes the idea of a spiritual family, showing that in the kingdom of God relationships are not limited only to biological ties. His question is not meant to show a lack of love toward his mother or his brothers, but aims to lift the conversation to a spiritual level, showing that his true family are those who do the will of God (as we will see in the next verse). This statement has deep significance: it affirms that in the Christian life, spiritual relationships, founded on faith and devotion to God, are to be preferred even over the closest family bonds.